Poster sessions
(preliminary, v. 18.09.2018)
Download the electronic version of the abstractbook here.
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No. wall |
Title of poster |
Authors |
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Poster session I |
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3D Models & Multi-Organ-Chips (MOC), Human-Organ-Chips (HOC) |
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| 1 | Sensitivity of CaCo-2 3D spheroids for fresh royal jelly (F-RY) (M) and HuIFN-αN3 | Bratko Filipič, CR-Zagreb, Klemen Rihar, SI-Ljubljana, Adriana Pereyra, SI-Ljubljana, Srećko Sladoljev, CR-Zagreb |
| 2 | Engineering of three-dimensional tissue constructs using our novel MagneTissue bioreactor as alternatives to animal models | Carina Hromada, AT-Vienna, Janine Tomasch, AT-Vienna, Anna Weihs, AT-Vienna, Dominik Rünzler, AT-Vienna, Andreas Teuschl, AT-Vienna |
| 3 | A novel co-culture system on skin sensitization for oil products | Huang Jiancong, CN |
| 4 | S. aureus-infection-model at human liver-on-chip | Fatina Siwczak, DE-Jena, Alexander Mosig, DE-Jena, Lorena Tuchscherr de Hauschopp, DE-Jena |
| 5 | Unique Animal Free 3D Culturing of Human Cancer Cells and Normal Cells | Atena Malakpour, SE-Lund, Plaurent Rocci, SE-Lund, Fredrik Johansson, SE-Lund |
| 6 | EpiIntestinal on a Chip: Label-free Microphysiometry of Intestinal Epithelium | Jan Markus, SK-Bratislava, Joachim Wiest, DE-Munich, Christian Schmidt, DE-Munich, Helena Kandarova, SK-Bratislava |
| 7 | Development of a human gut-on-chip model to study phagocyte dependent inflammatory response | Michelle Maurer, DE-Jena, Tony Wollny, DE-Jena, Florian Berlinghof, DE-Jena, Otmar Huber, DE-Jena, Alexander Mosig, DE-Jena |
| 8 | Liver bud formation using human upcyte cells | Nikolett Nagy, DE-Hamburg, Katja Breitkopf-Heinlein, DE-Mannheim, Haristi Gaitantzi, DE-Mannheim, Timo Johannssen, DE-Hamburg, Astrid Nörenberg, DE-Hamburg |
| 9 | A novel in vitro model of neuronal cultures based on 3D chitosan scaffold | Laura Pastorino, IT-Genova |
| 10 | Making drug screening visible: a human iPSC-derived biochip-based assay platform of the liver and kidney for real time assessment of drug toxicity | Martin Raasch, DE-Jena, Susanne Ackermann, DE-Jena, Anika Westphal, DE-Jena, Enrico Fritsche, DE-Berlin, Andreas Kurtz, DE-Berlin, Ralf Mrowka, DE-Jena, Alexander Mosig, DE-Jena |
| 11 | Establishment of a human alveolus-on-a-chip model to study microbial pathogenesis | Knut Rennert, DE-Jena, Stefanie Deinhardt-Emmer, DE-Jena, Sandor Nietzsche, DE-Jena, Bettina Löffler, DE-Jena, Alexander Mosig, DE-Jena |
| 12 | A human in vitro liver model for the investigation of inflammation and drug testing | Knut Rennert, DE-Jena, Marko Gröger, DE-Jena, Martin Raasch, DE-Jena, Julia Dinger, DE-Jena, Frank T. Peters, DE-Jena, Germany. Torsten Mayr, AT-Graz, Alexander Mosig, AT-Jena |
| 13 | Evaluation of a novel hydrostatic pressure bioreactor on bovine cartilage chips | Elias Salzer, AT-Vienna, Bernhard Rieder, AT-Vienna, Xavier Monforte Vila, AT-Vienna, Anna Weihs, AT-Vienna, Dominik Rünzler, AT-Vienna, Andreas Teuschl, AT-Vienna |
| 14 | Spatial defined cell characterization of a miniaturized heart tissue model | Stefan Stoiber, AT-Vienna, Michaela Purtscher, AT-Vienna, Barbara Gepp, AT-Vienna, Carina Huber-Gries, AT-Vienna |
| 15 | Strategy for the development of an advanced in vitro chordoma tumor model | Stefan Stoiber, AT-Vienna, Alexander Stallinger, AT-Graz, Bernadette Liegl-Atzwanger, AT-Graz, Cornelia Kasper, AT-Vienna, Beate Rinner, AT-Graz |
| 16 | Application of impedance spectroscopy for analysis of BeWo clone b30 human choriocarcinoma cell line as model of placenta-on-chip | Alexander Tonevitsky, RU-Moscow, Evgeny Knyazev, RU-Moscow, Sergey Nikulin, RU-Moscow, Sergey Nikulin, RU-Moscow, Tatyana Gerasimenko, RU-Moscow, Galina Zakharova, RU-Moscow, Ildar Gazizov, RU-Moscow, Dmitry Sakharov, RU-Moscow |
| 17 | Protein-to-lipid ratios determine dexamethasone penetration into skin and reconstructed human skin | Barbara Wanjiku, DE-Berlin, Kenji Yamamoto, DE-Berlin, André Klossek, DE-Berlin, Fabian Schumacher, DE-Nuthetal, Lars Mundhenk, DE-Berlin, Fiorenza Rancan, DE-Berlin, Munirrudin Ahmed, BD-Dhaka, Achim D. Gruber, DE-Berlin, Christian Zoschke, DE-Berlin, Burkhard Kleuser, DE-Nuthetal, Monika Schäfer-Korting, DE-Berlin, Eckart Rühl, DE-Berlin |
| 18 | EpiIntestinal on a Chip: Label-free Microphysiometry | Joachim Wiest, Munich, Christian Schmidt, DE-Munich, Jan Markus, SK-Bratislava, Helena Kandarova, SK-Bratislava |
| 19 | 3D NephroScreen: high throughput drug-induced nephrotoxicity screening on a proximal tubule-on-a-chip model | Karlijn Wilschut, NL-Leiden |
| 20 | Optimizing animal-free culture of primary human respiratory cells for live cell analyses | Viktoria Zaderer, AT-Innsbruck |
| 21 | Systems toxicology assessment of a 72-hour repeated exposure to Swedish snus extract and total particulate matter from 3R4F cigarette smoke on gingival organotypic cultures | Filippo Zanetti, CH-Neuchâtel, Alain Sewer, CH-Neuchâtel, Bjorn Titz, CH-Neuchâtel, Anita R. Iskandar, CH-Neuchâtel, Athanasios Kondylis, CH-Neuchâtel, Laura Ortega Torres, CH-Neuchâtel, Claudius Pak, CH-Neuchâtel, Florian Martin, CH-Neuchâtel, Emmanuel Guedj, CH-Neuchâtel, Ashraf Elamin, CH-Neuchâtel, Keyur Trivedi, CH-Neuchâtel, Stefan Frentzel, CH-Neuchâtel, Nikolai V. Ivanov, CH-Neuchâtel, Julia Hoeng, CH-Neuchâtel, Manuel C. Peitsch, CH-Neuchâtel |
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3R Centers in Europe - National and Local Centers |
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| 22 | The Danish National Committee for the Protection of Animals used for Scientific Purposes | Rasmus Normann Nielsen, DK-Copenhagen |
| 23 | The Danish 3R-Center | Rasmus Normann Nielsen, DK-Copenhagen |
| The Danish 3R-Center - supported projects | Rasmus Normann Nielsen, DK-Copenhagen | |
paid advertising
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3Rs in Education and Academia |
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| 24 | Introduction of the Core Facility Alternative Biomodels & Preclinical Imaging | Ines Anders, AT-Graz, Alexandra Lipfert, AT-Graz, Luka Brvar, AT-Graz, Silke Schrom, AT-Graz, Katharina Meditz, AT-Graz, Stefanie Wallner, AT-Graz, Beate Rinner, AT-Graz |
| 25 | The ROle of the University in Teaching and Education on ALTernative: ROUTE ALT | Francesca Caloni, IT-Milan, Alessia Bertero, IT-Milan |
| 26 | The 3Rs Database Programme: Humane Endpoints website, Interspecies Database and FCS-free Database | Saskia Kliphuis, NL-Utrecht, Pieter Verbost, NL-Utrecht, Jan van der Valk, NL-Utrecht |
| 27 | A decision tree – How are the 3Rs with algorithms applied in animal experiments? | Györgyi Szabó, HU-Budapest, Domokos Csukás, HU-Budapest, Andrea Ferencz, HU-Budapest, Krisztina Juhos, HU-Budapest, Daniella Fehér, HU-Budapest, József Sándor, HU-Budapest,György Wéber, HU-Budapest |
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Advanced Safety Testing of Cosmetics and Consumer Products |
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| 28 | The photostabilizer ethylhexyl methoxycrylene (EHMCR) affects the photostability and phototoxicity of sunscreens containing retinyl palmitate | Lorena Rigo Gaspar, BR-Ribeirão Preto |
| 29 | Relevance of in vitro test results to human data in safety and efficacy testing of cosmetics | Dagmar Jírová, CZ-Prague, Kristina Kejlova, CZ-Prague, Hana Bendova, CZ-Prague, Jan Chrz, CZ-Prague, Stanislav Janousek, CZ-Prague |
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Alternatives to Animal Testing in Food Safety, Nutrition and Efficacy |
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| 30 | Alternative Methods For Testing of Eye Irritation Caused by Agrochemicals | Istvan Buda, HU-Budapest, Peter Budai, HU-Keszthely, Jozsef Lehel, HU-Budapest, Gábor Hirka, HU-Balatonfüred |
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Biological Barriers |
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| 31 | A high throughput and cost-effective method to profile compounds interactions with efflux transporters using caco-2 cells line | Maxime Culot, FR-Lens, Emmanuel Sevin, FR-Lens, Lucie Dehouck, FR-Lens, Fabien Gosselet, FR-Lens |
| 32 | HIF-1 activation by oxyquinoline derivative in BeWo b30 monolayer as model of placental barrier hypoxia | Evgeny Knyazev, RU-Moscow, Andrey Poloznikov, RU-Moscow, Andrey Poloznikov, RU-Moscow, Diana Maltseva, RU-Moscow, Anna Khristichenko, RU-Moscow |
| 33 | Evaluation of In Vitro Models of the Rat and Human Airway Epithelium for Assessment of Acute Airway Toxicity | Hazel Simpson, GB-Edinburgh, Patrick Hayden, US-Ashland, George, R Jackson Jr, US-Ashland, Jo Vinall, GB-Edinburgh, Eleanor Storey, GB-Edinburgh, Michelle Debatis, US-Ashland, Anna Maione, US-Ashland, Clive Roper, GB-Edinburgh, Mitchell Klausner, US-Ashland |
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Disease Models Using HUMAN Cells, Tissues and Organs |
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| 34 | An in silico model on inflamed arthritic joints | Lisa Fischer, DE-Berlin |
| 35 | Organotypic head and neck cancer models for drug testing | Leonie Gronbach, DE-Berlin, Christopher Wolff, DE-Berlin, Konrad Klinghammer, DE-Berlin, Christian Zoschke, DE-Berlin, Ulrich Keilholz, DE-Berlin, Monika Schäfer-Korting, DE-Berlin |
| 36 | Two novel human myxofibrosarcoma cell lines represent a cellular model for tumor heterogeneity | Birgit Lohberger, AT-Graz, Nicole Stuendl, AT-Graz, Andreas Leithner, AT-Graz, Beate Rinner, AT-Graz, Stefan Sauer, AT-Graz, Karl Kashofer, AT-Graz, Bernadette Liegl-Atzwanger, AT-Graz |
| 37 | The impact of fibroblasts from atopic dermatitis patients on the epidermal differentiation of full-thickness skin equivalents | Anna Löwa*, DE-Berlin, Andrej Kováčik, CZ-Hradec Králové, Kateřina Vávrová, CZ-Hradec Králové, Sarah Hedtrich, DE-Berlin *awarded with the YSTA 2018 |
| 38 | Organotypic in vitro human airway models can recapitulate aspects of pulmonary fibrosis | Anna Maione, US-Ashland, George, R Jackson Jr, US-Ashland, Olivia O'Connel, US-Ashland, Jaclyn Webster, US-Ashland, Mitchell Klausner, US-Ashland, Silvia Letasiova, SK-Bratislava, Helena Kandarova, SK-Bratislava, Patrick Hayden, US-Ashland |
| 39 | Establishing endothelial cells derived from iPSCs for systemic sclerosis disease modeling and for in vitro vascular toxicity testing | Zahra Mazidi, AT-Vienna |
| 40 | Elucidation of Cytotoxic Effects of β-β-Dimethylacrylshikonin in Melanoma Cells | Alexander Stallinger, AT-Graz, Florian Kleinegger, AT-Graz, Ines Anders, AT-Graz, Bernadette Liegl-Atzwanger, AT-Graz, Birgit Lohberger, AT-Graz, Andreas Prokesch, AT-Graz, Christin Durchschein, AT-Graz, Nadine Kretschmer, AT-Graz, Alexander Deutsch, AT-Graz, Rudolf Bauer, AT-Graz, Beate Rinner, AT-Graz |
| 41 | A human epidermal burn wound model as alternative for animal testing | Verena Schneider, DE-Wuerzburg, Ives Bernardelli de Mattos, DE-Wuerzburg, Martin Funk, DE-Wuerzburg, Heike Walles, DE-Wuerzburg, Florian Groeber-Becker, DE-Wuerzburg, Florian Groeber-Becker, DE-Wuerzburg |
| 42 | The CAM Assay as alternative in vivo model system to study tumor aggressiveness | Regine Schneider-Stock, DE-Erlangen, Julienne K. Muenzner, DE-Erlangen, Markus Eckstein, DE-Erlangen |
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Ecotoxicology |
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| 43 | Investigation of endocrine effects of sublethal cadmium doses on the reproduction system of the freshwater snail B. glabrata | Katharina Eisner, AT-Vienna, Barbara Gepp, AT-Vienna, Raimund Schnegg, AT-Austria, Reinhard Dallinger, AT-Innsbruck, Dominik Rünzler, AT-Vienna |
| 44 | Pelargonic acid - an alternative to glyphosate-based herbicides? | Barbara Gepp, AT-Vienna, Varvara Liousia, AT-Vienna, Thomas Machacek, AT-Vienna, Daniela Praher, AT-Vienna, Katharina Eisner, AT-Vienna, Sophie Limbeck, AT-Vienna, Janine Gamper, AT-Vienna, Elisabeth Schwarzl, AT-Vienna, Till Hazod, AT-Vienna, Renate Landwehr, AT-Vienna, Lola-Charlotte Wenger, AT-Vienna, Christoph Olscher, AT-Vienna, Rita Leitner, AT-Vienna, Dominik Rünzler, AT-Vienna |
| 45 | Tracking of small aquatic organisms with custom-made tracking plates | Elias Salzer, AT-Vienna, Varvara Liousia, AT-Vienna, Xavier Monforte Vila, AT-Vienna, Dominik Rünzler, AT-Vienna |
| 46 | Environmental pollution: usefulness of different in vitro models to assess the effects of air and wastewaters on cell homeostasis. | Nathalie Steimberg, IT-Brescia, Jennifer Boniotti, IT-Brescia, Elena Vivenzi, IT-Brescia, Elena Lanfranchi, IT-Brescia, Donatella Feretti, IT-Brescia, Donatella Feretti, IT-Brescia, Ilaria Zerbini, IT-Brescia, Elisabetta Ceretti, IT-Brescia, Giorgio Bertanza, IT-Brescia, Roberta Pedrazzani, IT-Brescia, IT-Brescia, Umberto Gelatti, IT-Brescia, Giovanna Mazzoleni, IT-Brescia |
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Efficacy and Safety Testing of Drugs, Medical Devices & Biopharmaceutics |
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| 47 | Rapid Development of anti-idiotypic binders using a novel affinity scaffold | Dan Gare, GB-Wetherby |
| 48 | Progress towards the replacement of the rabbit blood sugar assay for quality control of insulins required by US Pharmacopeia (USP <121>) by an in vitro test | Rüdiger Hack, DE-Frankfurt, Sabrina Rueggeberg, DE-Frankfurt, Lea Schneider, DE-Frankfurt, Dirk Mayert, DE-Frankfurt, Norbert Tennagels, DE-Frankfurt, Stefan Welte, DE-Frankfurt, Birgit Niederhaus, DE-Frankfurt, Wilfried Arz, DE-Frankfurt, Dirk Usener, DE-Frankfurt, Goetz Troschau, DE-Frankfurt, Johannes Meiwes, DE-Frankfurt, Jochen Maas, DE-Frankfurt |
| 49 | Application of 3D liver microtissues for assessment of drug-induced liver injury (DILI) and for studying liver steatosis | Jan Lichtenberg, CH-Schlieren, Tomas Hejhal, InSphero, CH-Schlieren, Patrick Guye, InSphero AG, CH-Schlieren |
| 50 | Cytotoxic activity of six seaweed compounds, alone and in combination with doxorrubicin and cisplatin in a panel of human breast cell lines | Fernanda Malhão, PT-Porto, Alice Ramos, PT-Porto, Eduardo Rocha, PT-Porto |
| 51 | Development of an in-vitro testing battery to assess biocompatibility of medical devices | Elisabeth Mertl, AT-Vienna, Christian Kirchnawy, AT-Vienna, Daniela Neubert, AT-Vienna, Elisabeth Riegel, AT-Vienna, Thomas Czerny, AT-Vienna |
| 52 | Cytotoxicity of secondary metabolites from the marine-derived fungus talaromyces stipitatus kufa 0207 in a melanoma cell line | Alice Ramos, PT-Porto, Sofia Mateus, PT-Porto, PT-Porto, Tida Dethoup, TH-Bangkok, Anake Kijjoa, PT-Porto, Eduardo Rocha, PT-Porto |
| 53 | Cytotoxic activity of the seaweed compound fucosterol, alone and in combination with 5-fluorouracil in colon cells | Alice Ramos, PT-Porto, Tânia Almeida, PT-Porto, Bruna Lima, PT-Coimbra, Eduardo Rocha, PT-Porto |
| 54 | In vitro anticancer activity of preussin, a hydroxypyrrolidine alkaloid, isolated from the marine sponge-associated fungus aspergillus candidus kufa 0062 in breast cancer cell lines | Alice Ramos, PT-Porto, Fernanda Malhão, PT-Porto, Suradet Buttachon, PT-Porto, Tida Dethoup, TH-Bangkok, Anake Kijjoa, PT-Porto, Eduardo Rocha, PT-Porto |
| 55 | Human primary fibroblasts versus immortalized Balb/c mouse 3T3 fibroblasts for cytotoxicity and LD50 prediction | Renata Spagolla Napoleão Tavares, BR-Ribeirão Preto, Lorena Rigo Gaspar Cordeiro, BR-Ribeirão Preto |
| 56 | Detection of antibodies in animal serum samples using by Surface Plasmon Resonance biosensor | Alla Yushchenko, UA-Kyiv, Glib Dorozhyns’kyi, UA-Kyiv, Yulia Dremuch, UA-Kyiv, Yurii Ushenin, UA-Kyiv, Zinaida Klestova, UA-Kyiv, Sergii Kravchenko, UA-Kyiv, Volodymyr Maslov, UA-Kyiv, Nataliia Gavrasieva, UA-Kyiv, Oksana Blotskaya, UA-Kyiv |
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Poster session II |
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Free Communications |
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| 57 | Highly relevant human in vitro cell models grown under serum-free culture conditions | Matthias Wieser, AT-Vienna, Susanne Neubert, AT-Vienna, Pascal Zimmermann, DE-Aidenbach, Jianan Fu, DE-Aidenbach, Josef Seidl, DE-Aidenbach, Johannes Grillari, AT-Vienna, Regina Grillari, AT-Vienna |
| 58 | Implementing the 3Rs into ecological research | Miriam A. Zemanova, CH-Basel |
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In Silico Models: Toxicology & Efficacy of Drugs, Chemicals & Cosmetics |
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| 59 | An in silico approach to predict aromatase toxicity for azoles | Ana Caballero, IT-Milan, Chayawan Chayawan, IT-Milan, Emilio Benfenati, IT-Milan |
| 60 | MechoAs (Mechanism of Action) QSAR Model and Skin Sensitization Screening: 3-methoxyphenols, 4-methoxyphenol and 1,4-dimethoxybenzene case study. | Melanie Delannoy, FR-L'Isle d'Abeau, Franklin Bauer, FR-L'Isle d'Abeau, Carole Charmeau-Genevois, FR-L'Isle d'Abeau, Paul Thomas, FR-L'Isle d'Abeau |
| 61 | Reverse dosimetry approaches for potential endocrine disruptors: | Eric Fabian, DE-Ludwigshafen, Amelie Ochs, DE-Ludwigshafen, Christian Haase, DE-Ludwigshafen, Caroline Gomes, DE-Ludwigshafen, Barbara Birk, DE-Ludwigshafen, Tzutzuy Ramirez, DE-Ludwigshafen, Rene Zbranek, DE-Ludwigshafen, Bennard van Ravenzwaay, DE-Ludwigshafen, Robert Landsiedel, DE-Ludwigshafen |
| 62 | Use of publicly available transcriptomics data to support the steatosis AOP development | Oana Florean, CH-Basel, Lucian Farcal, CH-Basel, Noffisat Oki, CH-Basel, Thomas Exner, CH-Basel, Barry Hardy, CH-Basel, Tatyana Doktorova, CH-Basel |
| 63 | Establishment of an In Silico Model for Drug-Target Interaction Analysis, Drug Efficacy Screening and Drug Design | Maximilian Fuchs, DE-Wuerzburg, Meik Kunz, DE-Wuerzburg, Thomas Dandekar, DE-Wuerzburg |
| 64 | Estrogen and androgen receptor binding affinity of bisphenols estimated by QSAR | Kristina Kejlova, CZ-Prague, Marian Rucki, CZ-Prague, Marketa Dvorakova, CZ-Prague, Dagmar Jírová, CZ-Prague |
| 65 | P-glycoprotein modelling: in silico classification model of P-glycoprotein interacting compounds | Liadys Mora Lagares, SI-Ljubljana, Marjana Novič, SI-Ljubljana, Nikola Minovski, SI-Ljubljana |
| 66 | In-silico tool to design cyp3a5 silensomestm using T-5 substrate and lapatinib as mechanism-based inhibitor | Ashwani Sharma, FR-Saint-Grégoire, Damien Thomas, FR-Saint-Gregoire, Solenne Martin, FR-Saint-Gregoire, Françoise Bree, FR-Saint Gregoire, Sylvain Routier, FR-Orleans, Christophe Chesne, FR-Saint Gregoire |
| 67 | Establishment of an In Silico Model to Understand Adrenocortical Carcinoma and Preclinical Drug Screening | Johannes Vey, DE-Wuerzburg, Meik Kunz, DE-Wuerzburg, Matthias Kroiss, DE-Wuerzburg, Martin Fassnacht, DE-Wuerzburg, Thomas Dandekar, DE-Wuerzburg |
paid advertising
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International Progress in 3Rs Research |
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| 68 | AIVIS 1.1 – Let´s draw future! | Martin Paparella, AT-Innsbruck, Johanna Gostner, AT-Innsbruck, Josef Zelger, AT-Innsbruck |
| 69 | The European Consensus Platform for 3R Alternatives to Animal Experimentation (ecopa) | Costanza Rovida, DE-Konstanz, Luisa Bastos, BE-Brussels, Philippe Hubert, FR-Paris, Tuula Heinonen, FI-Tampere |
| 70 | The human hepatic HepaRG cells combined with PBPK modellings as first practical efforts towards modern toxicology and the 3Rs in Tunisia | Raoudha Sadraoui, TN-Zarroug Gafsa |
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In vitro Techniques for CNS Toxicity and Disease Studies |
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| 71 | Development of a cellular neurotoxicology model using genetically engineered human induced pluripotent stem cells, a 3Rs alternative to animal testing. | Aurore Bourguignon*, HU-Gödöllő, Julianna Kobolak, HU-Gödöllő, Zofia Janstova, HU-Gödöllő, István Bock, HU-Gödöllő, Anita Fehér, HU-Gödöllő, Andras Dinnyes, HU-Gödöllő *awarded with the YSTA 2018 |
| 72 | As exposure confers resilience to proteotoxicity in a C. elegans model of Alzheimer´s disease | Miguel Chin-Chan, DE-Jena, Maria A. Ermolaeva, DE-Jena |
| 73 | Modelling Alzheimer’s disease in three-dimensional human neural progenitor cultures | Carine Gaiser, CH-Muttenz, Anna Weston, CH-Muttenz, Laura Suter-Dick, CH-Muttenz |
| 74 | Toxicogenomics reveals neuronal specific and non-specific responses to cadmium possibly involved in neurodegeneration | Chiara Urani, IT-Milan, Matilde Forcella, IT-Milan, Pierre Lau-Poui-CheungIT-Ispra, Alessia Bogni, IT-Ispra, Pasquale Melchioretto, IT-Milan, Laura Gribaldo, IT-Ispra, Paola Fusi, IT-Milan |
| 75 | BBB on-a-chip: a 3D in vitro model of the human blood brain barrier (BBB) | Karlijn Wilschut, NL-Leiden |
| 76 | Monitoring neurotransmitter release from human Midbrain Organoids (hMOs) supernatant using an electrochemical redox cycling microsensor | Cristian Zanetti, AT-Vienna, Jens Schwamborn, LU-Luxembourg, Peter Ertl, AT-Vienna |
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Refinement & Reduction I- Culture of Care and Translational Research |
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| 77 | EFPIA - Putting animal welfare principles and 3Rs into action | Thomas Bertelsen, DK-Maaloev, Kirsty Reid, BE-Brussels, Chris Petursson, US-Lawrence |
| 78 | Does lidocaine-bupivacaine as a local anesthetic reduce postoperative pain perception and improve overall wellbeing? | Mattea Durst, CH-Zurich, Margarete Arras, CH-Zurich, Paulin Jirkof, CH-Zurich, |
| 79 | Tramadol:Paracetamol in drinking water to treat post-surgical pain in laboratory mice | Paulin Jirkof, CH-Zurich, Margarete Arras, CH-Zurich, Nikola Cesarovic, CH-Zurich |
| 80 | Benefits of combining positive reiforcement training and social observation in laboratory rats | Charlotte Sophie Leidinger, DE-Mainz, Nadine Baumgart, DE-Mainz, Jan Baumgart, DE-Mainz |
| 81 | Different mouse strains – different nesting materials. Searching for the perfect refinement in the housing of mice | Beate Obermüller, AT-Graz, Birgit Reininger-Gutmann, AT-Graz |
| 82 | The RepRefRed Society | Birgit Reininger-Gutmann, AT-Graz, Roberto Plasenzotti, AT-Vienna, Beate Rinner, AT-Graz, Doris Wilflingseder, AT-Innsbruck |
| 83 | Motivation by restriction? - Starting points for controlled fluid and food intake in neurocognitive research from a 3Rs perspective | Marjolein Schilders-van Boxel, NL-Den Haag, Coenraad Hendriksen, NL-Den Haag, Wim de Leeuw, NL-Den Haag, Herman Koeter, NL-Den Haag, Henriette Bout, NL-Den Haag, Jan-Bas Prins, NL-Den Haag, Pieter Roelfsema, NL-Den Haag, Reineke Hameleers, NL-Den Haag, Leane van Weereld, NL-Den Haag |
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Replacement – Advanced Technologies for Implementation of 3Rs |
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| 84 | Microstructured thermoresponsive cell culture substrates for the controlled formation of oriented neuronal networks in vitro | Laura Behm, DE-Berlin, Susanna Gerike, DE-Berlin, Felix Pfisterer, DE-Potsdam, Philipp Wysotzki, DE-Rostock, Katja Uhlig, DE-Potsdam, Werner Baumann, DE-Rostock, Frank Bier, DE-Potsdam, Frank Bier, DE-Potsdam, Claus Duschl, DE-Potsdam, Michael Kirschbaum, DE-Potsdam |
| 85 | Optimization of the Gluc-HET model | Renate Haselgrübler, AT-Wels, Flora Stübl, AT-Wels, Marcus Iken, LU-Schengen, Klaus Schröder, AT-Linz, Julian Weghuber, AT-Wels |
| 86 | Introduction of a silicone embryo model for teaching in biomedical research | Maximilian Nuber, DE-Mainz, Meik Neufurth, DE-Mainz, Felix Herrmann, DE-Mainz, Nadine Baumgart, DE-Mainz, Jan Baumgart, DE-Mainz |
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Specific Endpoints of Toxicity |
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| 87 | Establishment of in vitro exposure system for safety study of theatrical fogs | Sasitorn Aueviriyavit, TH-Pathum Thani, Apiwan Rosena, TH-Pathum Thani, Arisara Prateep, TH-Pathum Thani, Chaweewan Sapcharoenkun, TH-Pathum Thani, Onuma Ketchart, TH-Pathum Thani, Panita Kasamechonchung, TH-Pathum Thani, Rawiwan Maniratanachote, TH-Pathum Thani |
| 88 | Avoiding false positive results of the in vitro Micronucleus Assay in order to reduce Follow-Up studies in vivo | Naveed Honarvar, DE-Ludwigshafen |
| 89 | Integration of emerging In Vitro assays into Skin Sensitisation Assessment Strategy | Gitta Katona, HU-Balatonfüred, Viktória Kocsi, HU-Balatonfüred, Mária Pénzes, HU-Balatonfüred, Gábor Hirka, HU-Balatonfüred |
| 90 | Assessment of contact sensitization potential of 20 chemicals using in vitro reconstructed normal human epidermal model EpiDerm: impact of the modality of application | Silvia Letasiova, SK-Bratislava, Emanuela Corsini, IT-Milan, Valentina Galbiati, IT-Milan, Helena Kandarova, SK-Bratislava |
| 91 | Assay ready frozen THP-1 cells can be used like a reagent in a human Cell Line Activation Test (h-CLAT) to measure the skin sensitizing potential of chemicals. | Vladimir Mazurov, DE-Hamburg, Julie Walbech, DE-Hamburg, Alexander Loa, DE-Hamburg, Oliver Wehmeier, DE-Hamburg |
| 92 | Predicting human lung toxicity induced by aerosols released from thermal utilization of polymer nanocomposites using human alveolar epithelial A549 cells and the human 3D airway model MucilAir™ | Nadja Wingert, DE-Freiburg, Matthias Hufnagel, DE-Karlsruhe, Nadine Teuscher, DE-Karlsruhe, DE-Karlsruhe, Sonja Mülhopt, DE-Karlsruhe, Werner Baumann, DE-Karlsruhe, Hanns-Rudolf Paur, DE-Karlsruhe, Markus Berger, DE-Waldkirch, Christoph Schlager, DE-Waldkirch, Tobias Krebs, DE-Waldkirch, Ali Arif, DE-Freiburg, Manuel Garcia-Käufer, DE-Freiburg, Richard Gminski, DE-Freiburg |
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Update on Implementing EU Dir 63/2010 |
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| 93 | The UK must adopt the EU’s final goal of full replacement of procedures on live animals for scientific and educational purposes | Anna van der Zalm, GB-London, Julia Baines, GB-London |
| 94 | Recommendations to improve non-technical summaries of animal experiments | Tilo Weber, DE-Neubiberg, Laura Rego, GB-London, Katy Taylor, GB-London |
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Vaccines & The 3Rs: New Methods and Developments |
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| 95 | MTS application to Italian veterinary autogenous vaccines as alternative in vitro method to assess citotoxicity: preliminary data. | Antonella Di Paolo, IT-Perugia, Katia Forti, IT-Perugia, Lucia Anzalone, IT-Perugia, Giulio Severi, IT-Perugia, Monica Cagiola, IT-Perugia |
| 96 | International harmonisation: Progress in establishing VICH guidelines on waiving criteria for general batch safety tests of veterinary vaccines | Marlies Halder, IT-Ispra, Esther Werner, DE-Langen |
| 97 | Recommendations of the VAC2VAC workshop on optimising the design of multi-centre validation studies | Marlies Halder, IT-Ispra, Hilde Depraetere, DE-Heidelberg, Frédérique Delannois, BE-Rixensart, Carmen Jungbaeck, FR-Lyon, Peter Rigsby, GB-Potters Bar, Catrina Stirling, GB-Walton Oaks, Coenraad Hendriksen, NL-Bilthoven, Ruediger Raue, BE-Zaventem |
| 98 | Validation of an in vitro assay for the detection of residual viable rabies virus in inactivated rabies vaccines. | Beatriz Moreira*, BR-Curitiba, Beatriz Moreira, BR-Curitiba, Ana Paula Lappas Gimenez Sbalqueiro, BR-Curitiba, Jorge Minor Inagaki, BR-Curitiba, Sonia Mara Raboni, BR-Curitiba *awarded with the YSTA 2018 |
| 99 | A kinomics approach to safety testing: towards an animal-free safety test for whooping cough vaccines | Saertje Verkoeijen, NL-Utrecht, Kitty van Summeren, NL-Utrecht, Marc Teunis, NL-Utrecht, Cyrille Krul, NL-Utrecht |
